EARLY CONSUMPTION OF HIBISCUS SABDARIFA ATTENUATES THE SEVERITY OF TYPE 2 DIABETES IN A WISTAR RAT MODEL

Diabetes constitute a serious challenge for many health system and families due to the cost of its care. Alternatively, traditional plants offer huge potential Thus, have been used in form beverage including use Hibiscus sabdarifa (HS) as tea. Recent data suggested beneficial effect HS cardiometabolic diseases models. In this study, we evaluated preventive curative effects crude extract type 2 diabetes rat model. Through vitro complexion and/ or precipitation reactions, qualitatively assessed phytochemical composition different groups secondary metabolites. The antiradical scavenging activity was through hydroxyl radical test. Type induced by high fat diet (HFD) single dose streptozotocine (STZ) injection. Body weight change blood biochemical analysis were carried out. Data statistically analyzed. contains polyphenolic compounds such tanins flavonoids presented an interesting activity. Early intake from experimental day (ED1) significantly prevented gain body (P < 0.05), reduced T2D elevated glucose 0.01) lipids has better outcome compared late (from ED14). These findings confirm supports tea may protective consumers regulating sugar lipid profile.